WebIntroduction. Glial-derived tumor, or glioma, is the most common brain tumor and accounts for about 74.6% of all malignant tumors occurring in brain and central nervous system. 1 Approximately 82% of gliomas cases are diagnosed at high malignant WHO grades III and IV, with a 5-year survival rate of only 10%. 2 It is identified that radiotherapy has synergistic … WebThis SMURF1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 66-96 amino acids from the N-terminal region of human SMURF1. Dilution : WB~~1:2000 IHC-P~~1:10~50: Format : Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is prepared by Saturated Ammonium …
SMURF1 Antibody (H00057154-D01P): Novus Biologicals
Web18 Oct 2002 · In thebottom panel, aliquots of cell lysates were directly subjected to immunoblotting with anti-Myc antibody to confirm the expression of Smurf1(WT) or Smurf1(ΔC2). B, Smurf1(WT) but not Smurf1(ΔC2) reduced steady-state levels of the mature form of TβR-I in vivo. COS7 cells were transfected with the indicated plasmids. Web20 Mar 2024 · Smurf1, a HECT domain E3 ubiquitin ligase, regulates cell polarity and protrusive activity and is required to maintain the transformed morphology and motility of a tumor cell. Atypical protein kinase C-zeta (PKC2), an effector of the Cdc42/Rac1-PAR6 polarity complex, recruits Smurf1 to cellular protrusions, where it controlled the local level … crisp and green thai and stop me
SMURF1 antibody (55175-1-AP) Proteintech - ptglab
Web29 Dec 2024 · Smurf1 and RhoA could be detected in the whole cell lysates of all groups, suggesting that the whole cell lysates could be used for subsequent Co-IP experiments. When Smurf1 antibody was used to pull down the protein complex, RhoA expression was detected in the control group (Smurf1−/RhoA−), while Ub expression was low. WebTargetMol的所有产品和服务仅用于科学研究，不能被用于人体，我们也不向个人提供产品和服务。. 我们的产品含有多种规格，如需了解具体的规格以及价格信息，请联系我们咨询订购，对于大额的订购，我们还有额外的优惠！. 特别折扣等您来询! 如果上述化合物 ... Web26 Dec 2006 · To characterize the role of Smurf1 in MDAMB-231 breast cancer cells, we reduced its expression by using siRNAs or short hairpin RNAs (shRNAs) targeting different sequences in the smurf1 gene (). siRNA or shRNA silencing was accompanied by cell rounding, a reduction in size, and a loss of membrane protrusions.Accordingly, silenced … crisp and green st paul mn