Drug itga6
WebITGA6 is part of cluster 66 Endothelial cells - Angiogenesis with confidence i Confidence is the fraction of times a gene was assigned to the cluster in repeated clustering, and … Web15 dic 2024 · In mechanism, ITGA6 was a target of miR-126, and exosomal miR-126 weakened these NSCLC cell malignant behaviors and inhibited tumor growth by degrading the expression of ITGA6. Exosomal miR-126 blocked the progression of NSCLC through the mediation of its target gene ITGA6, and exosomal miR-126 might be used as a …
Drug itga6
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WebShowing tissue cell type specific RNA data of ITGA6 (CD49f). We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again. ITGA6. ... The ITGA6 protein product is the integrin alpha chain alpha 6. Integrins are integral cell-surface proteins composed of an alpha chain and a beta chain. A given chain may combine with multiple partners resulting in different integrins. For example, alpha 6 may combine with beta 4 in the integrin referred to as … Visualizza altro Integrin alpha-6 is a protein that in humans is encoded by the ITGA6 gene. Visualizza altro ITGA6 has been shown to interact with TSPAN4 and GIPC1. Visualizza altro • Lipscomb EA, Mercurio AM (September 2005). "Mobilization and activation of a signaling competent alpha6beta4integrin underlies its contribution to carcinoma progression". … Visualizza altro • Cluster of differentiation • Integrins Visualizza altro • CD49f+Antigen at the U.S. National Library of Medicine Medical Subject Headings (MeSH) • ITGA6 Info with links in the Cell Migration Gateway Archived 11 December … Visualizza altro
WebITGA6. General description of the gene and the encoded protein (s) using information from HGNC and Ensembl, as well as predictions made by the Human Protein Atlas project. Official gene symbol, which is typically a … WebIntegrin alpha-6/beta-1 (ITGA6:ITGB1) is a receptor for laminin on platelets (By similarity). Integrin alpha-6/beta-1 (I TGA6:ITGB1) is present in oocytes and is involved in sperm …
Web20 feb 2024 · Integrin α‑6 (ITGA6) is a member of the adhesion molecule family that conducts signals through interactions between the extracellular domain and the matrix, serving important roles in cell adhesion‑mediated drug resistance, which is considered to have a critical function in ovarian cancer drug resistance. Web25 gen 2012 · The expression of ITGA6 is significantly elevated in cells from relapsed and EVI1high AML cases; therefore, ITGA6 might represent an important therapeutic target …
Web24 feb 2024 · ITGA6 integrin subunit α6, PKM pyruvate kinase, Bcl B-cell lymphoma, VEGF vascular endothelial growth factor, TAK1 TGF-β-activated kinase 1, CD44 cluster of …
Web18 giu 2024 · Deregulation of integrins signaling had been documented to participate in various processes of cancer, including but not limited to tumor initiation, metastatic cascade, and drug resistance . Given their critical roles in multiple fundamental biological processes, the aberrant expression of integrin family members were linked to the prognosis of … sign in to 1 driveWeb25 gen 2012 · In this study, we determined whether the increased expression of ITGA6 is associated with drug-resistance and increased cell adhesion, resulting in poor prognosis. sign in to access this site bypassWebOur results demonstrate an oncogenic role of m6A-modified ITGA6 and show its regulatory mechanisms in BC development and progression, thus identifying a potential therapeutic target for BC. FUND: This work was supported by National Natural Science Foundation of China (81772699, 81472999). sign in to access your ebook yuzu contentWebITGA6 is significantly elevated in cells from relapsed and EVI1high AML cases; therefore, ITGA6 might represent an important therapeutic target for both refractory and EVI1high … sign in to access this site popup in edgeWebITGA6 might be involved in a mechanism that underlies radiation resistance and that ITGA6 could be a potential target for therapies aimed at overcoming radiation resistance in … sign in to account huluWebNational Center for Biotechnology Information sign in to 30 hours free childcareWebIntegrin alpha-6/beta-4 (ITGA6:ITGB4) is a receptor for laminin in epithelial cells and it plays a critical structural role in the hemidesmosome (By similarity). ITGA6:ITGB4 binds to … sign in to 365 office