WebJan 17, 2012 · Cullin-3 (Cul3) functions as a scaffolding protein in the Bric-a-brac, Tramtrack, Broad-complex (BTB)-Cul3-Rbx1 ubiquitin E3 ligase complex. Here, we report a previously undescribed role for Cul3 complexes in late endosome (LE) maturation. RNAi-mediated depletion of Cul3 results in a trafficking def … Web该KCTD16 Polyclonal Antibody. The BTB (Broad-Complex, Tramtrack and Bric a brac) domain, also known as the POZ (Poxvirus and Zinc finger) domain, is an N-terminal homodimerization domain that contains multiple copies of kelch repeats and/or C2H2-type zinc fingers. Proteins that contain BTB domains are thought to be involved in …
CDD Conserved Protein Domain Family: BTB - National Center …
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WebEasily access important information about your Ford vehicle, including owner’s manuals, warranties, and maintenance schedules. WebJun 10, 2005 · The BTB domain (also known as the POZ domain) was originally identified as a conserved motif present in the Drosophila melanogaster bric-à-brac, tramtrack and broad complex transcription regulators and in many pox virus zinc finger proteins [1–4].A variety of functional roles have been identified for the domain, including transcription … WebA cell-permeable oxindole compound that selectively inhibits the transcriptional repression activity of BCL6 (by ~70% at 50 µM in 293T-based reporter assays), but not that of three other BTB/POZ (bric-a-brac tramtrack broad complex/Poxvirus zinc finger) family members, Kaiso, HIC1, and PLZF, by direct BCL6 binding (K d = 138 µM) via the BTB ... sbw vs mark hunt fight